GRIK3

Across TCGA cell cohorts, GRIK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,537 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GRIK3-associated GO terms across cancer lineages are Adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway, Chromosomal 5-methylcytosine DNA demethylation pathway, and Intestinal lipid absorption. Each is linked with GRIK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRIK3-to-partner and partner-to-GRIK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway grouped by GRIK3-low versus GRIK3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK3→partner) and Y-score (partner→GRIK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway →	+1.715	+3.082	<.001	<.001	3	7
BONE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.127	+2.671	.001	.001	2	7
BONE	Intestinal lipid absorption →	-0.257	-1.826	<.001	.007	3	6
BREAST	Regulation of coagulation →	-0.187	-1.787	<.001	<.001	3	5
BONE	Pancreas development →	-0.102	-1.465	<.001	.008	3	5
BONE	Zymogen activation →	-0.223	-1.797	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,537 associations by consensus.

Adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway by GRIK3 expression — LUNG_SCLC

Explore this box plot interactively →