GRIK1-AS1

Across TCGA pan-cancer cohorts, GRIK1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GRIK1-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher GRIK1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GRIK1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

UVM, HNSC, and KIRC are the cancer types where GRIK1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.312	0.668	<.001	131	view →
HNSC	OS	Quartile	III,IV	0.587	0.296	.001	107	view →
KIRC	DFS	Median	All	0.503	0.721	<.001	71	view →
UCS	OS	Median	All	0.840	0.511	.001	42	view →
BRCA	OS	Median	All	0.976	0.948	.001	35	view →
READ	DFS	Tertile	III,IV	0.509	0.191	.005	35	view →
LUSC	OS	Median	All	0.316	0.478	.003	30	view →
SKCM	OS	Tertile	IV	0.854	0.393	.002	21	view →
OV	DFS	Quartile	IV	0.260	0.573	.008	20	view →
COAD	DFS	Tertile	All	0.403	0.587	.012	17	view →
LIHC	OS	Tertile	All	0.622	0.825	<.001	16	view →
KICH	DFS	Median	III,IV	0.462	1.000	.027	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GRIK1-AS1–UVM (DFS)

Open the UVM breakdown →