GRIK1-AS1

Across TCGA pan-cancer cohorts, GRIK1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of GRIK1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GRIK1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types GRIK1-AS1 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

COAD, THCA, and BRCA are the cancer types where GRIK1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRIK1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.211	<.001	8	view →
THCA	All	II,III,IV	+0.080	<.001	7	view →
BRCA	Female	All	−1.266	<.001	6	view →
KIRP	Male	III,IV	−0.206	.002	6	view →
KICH	Female	All	−0.412	<.001	5	view →
BLCA	All	All	−0.376	.011	5	view →
KIRC	Female	IV	−0.333	.006	4	view →
READ	All	All	−0.305	.006	2	view →
LUSC	All	All	+0.177	.019	2	view →
PRAD	All	All	−0.104	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

GRIK1-AS1–COAD

Open the COAD breakdown →