Across TCGA cell cohorts, GRID2IP mutation is significantly associated with the mutation status of many other genes, with 4,787 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRID2IP-associated genes across cancer lineages are ARID2, ZNF611, and MEGF8. Each is linked with GRID2IP in more than 4 cancer types. Because this analysis shows association rather than direction, both GRID2IP-to-partner and partner-to-GRID2IP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2IP→partner) and Y-score (partner→GRID2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ARID2 →	+2.584	+2.493	.009	.009	1	5
BLOOD_Leukemia	ZNF611 →	+3.247	+3.050	.008	.008	1	4
LARGE_INTESTINE	MEGF8 →	+1.636	+1.963	.003	.003	1	4
LARGE_INTESTINE	LRRC4B →	+2.148	+1.989	.003	.003	1	4
LARGE_INTESTINE	ANKS1B →	+1.604	+1.777	.007	.007	1	4
LARGE_INTESTINE	RC3H2 →	+1.925	+1.857	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,787 associations by consensus.

Exploration

GRID2IP survival (RNA) · tumor vs normal (RNA) · all GRID2IP data types