GRID2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRID2 protein abundance is significantly associated with the RNA expression of many other genes, with 401 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRID2-associated genes across cancer lineages are RAB36, CHADL, and TUBB1. Each is linked with GRID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRID2-to-partner and partner-to-GRID2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRID2 versus RAB36 in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2→partner) and Y-score (partner→GRID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRAB36 →-0.541-0.248.001.00731
GBMCHADL →+0.941+0.433.003.00231
GBMTUBB1 →+0.450+0.446<.001<.00131
GBMCDH20 →+1.179+0.439<.001<.00131
GBMKLF5 →-0.803-0.460<.001<.00131
GBMABCC1 →-0.356-0.298.009.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 401 associations by consensus.

GRID2 vs RAB36 — GBM

Per-sample scatter of GRID2 vs RAB36 in GBM (Pearson r = -0.37).

Explore this scatter interactively →

Exploration