GRID2

Across TCGA patient cohorts, GRID2 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,058 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRID2-associated proteins across cancer lineages are ASIC4, ASTN1_S379, and ATRX_S66. Each is linked with GRID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRID2-to-partner and partner-to-GRID2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRID2 versus ASIC4 in GBM, with a Pearson correlation of 0.35.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2→partner) and Y-score (partner→GRID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASIC4 →	+0.709	+0.368	<.001	<.001	3	1
GBM	ASTN1_S379 →	+0.658	+0.513	<.001	<.001	3	1
GBM	ATRX_S66 →	-0.639	-0.537	<.001	<.001	3	1
GBM	BAD_S134 →	-0.322	-0.445	<.001	<.001	3	1
GBM	BPGM →	+0.409	+0.329	<.001	<.001	3	1
GBM	BTBD8_S290 →	+0.611	+0.605	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,058 associations by consensus.

GRID2 vs ASIC4 — GBM

Explore this scatter interactively →