GRID2

Across TCGA cell cohorts, GRID2 RNA expression is significantly associated with the go_rna of many other GO terms, with 817 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GRID2-associated GO terms across cancer lineages are Regulation of postsynaptic specialization assembly, Cytoplasmic translation, and Regulation of postsynaptic membrane potential. Each is linked with GRID2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRID2-to-partner and partner-to-GRID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynaptic specialization assembly grouped by GRID2-low versus GRID2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2→partner) and Y-score (partner→GRID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of postsynaptic specialization assembly →	-0.061	-0.319	<.001	<.001	3	6
PANCREAS	Cytoplasmic translation →	+0.057	+0.030	.004	.004	2	6
PANCREAS	Regulation of postsynaptic membrane potential →	-0.132	-0.032	<.001	.003	3	4
SKIN	Sensory perception of itch →	-0.516	-0.283	.001	.003	3	4
LARGE_INTESTINE	Heterochromatin formation →	+0.043	+0.011	<.001	.005	3	4
LARGE_INTESTINE	Epigenetic regulation of gene expression →	+0.036	+0.011	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 817 associations by consensus.

Regulation of postsynaptic specialization assembly by GRID2 expression — SKIN

Explore this box plot interactively →