GRID1-AS1

Across TCGA pan-cancer cohorts, GRID1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GRID1-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher GRID1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GRID1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LAML show a favorable association.

UVM, STAD, and KIRP are the cancer types where GRID1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.312	0.701	<.001	117	view →
STAD	OS	Tertile	II,III,IV	0.378	0.650	.001	89	view →
KIRP	DFS	Tertile	All	0.718	0.894	<.001	64	view →
UCEC	OS	Tertile	III,IV	0.898	0.539	.022	54	view →
LUSC	DFS	Tertile	II,III,IV	0.247	0.402	.005	48	view →
LAML	DFS	Quartile	All	0.636	0.307	<.001	40	view →
COAD	DFS	Tertile	IV	0.180	0.582	.007	33	view →
LIHC	OS	Tertile	All	0.556	0.734	.012	27	view →
SKCM	DFS	Tertile	II,III,IV	0.120	0.249	.004	24	view →
LUAD	OS	Tertile	All	0.785	0.630	.011	24	view →
LGG	OS	Tertile	All	0.546	0.325	<.001	23	view →
HNSC	OS	Tertile	II,III,IV	0.484	0.318	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

GRID1-AS1–UVM (DFS)

Open the UVM breakdown →