GRID1-AS1

Across TCGA pan-cancer cohorts, GRID1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of GRID1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GRID1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GRID1-AS1 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

KIRC, LUSC, and THCA are the cancer types where GRID1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRID1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.017	<.001	8	view →
LUSC	Male	All	−0.026	.004	3	view →
THCA	All	II,III,IV	−0.083	.041	2	view →
LUSC	Female	III,IV	+0.045	.012	1	view →
LUAD	All	III,IV	−0.024	.047	1	view →
BLCA	All	III,IV	+0.016	.041	1	view →
LIHC	Male	All	+0.008	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 6 lineages.

GRID1-AS1–KIRC

Open the KIRC breakdown →