GRIA4

Across TCGA patient cohorts, GRIA4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,457 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIA4-associated genes across cancer lineages are SEC14L2, CRYBB3, and CYTH4. Each is linked with GRIA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIA4-to-partner and partner-to-GRIA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIA4 versus SEC14L2 in GBM, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIA4→partner) and Y-score (partner→GRIA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	+0.456	+0.428	.005	.002	3	1
GBM	CRYBB3 →	+0.303	+0.326	.007	.008	3	1
GBM	CYTH4 →	-0.798	-0.577	<.001	.002	3	1
GBM	SEZ6L →	+1.708	+0.516	<.001	<.001	3	1
GBM	LGALS1 →	-0.562	-0.545	<.001	<.001	3	1
GBM	PATZ1 →	+0.386	+0.413	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,457 associations by consensus.

GRIA4 vs SEC14L2 — GBM

Explore this scatter interactively →