GRIA4

Across TCGA cell cohorts, GRIA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,177 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRIA4-associated GO terms across cancer lineages are Peptidyl-amino acid modification, Regulation of nucleotide-excision repair, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with GRIA4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GRIA4-to-partner and partner-to-GRIA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-amino acid modification grouped by GRIA4-low versus GRIA4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIA4→partner) and Y-score (partner→GRIA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Peptidyl-amino acid modification →	+0.037	+1.500	<.001	.001	3	9
PANCREAS	Regulation of nucleotide-excision repair →	+0.066	+0.041	<.001	.009	3	8
LUNG_NSCLC_LUSC	Regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.285	<.001	.009	2	8
PANCREAS	Regulation of neurotransmitter transport →	-0.053	-0.039	.003	<.001	3	7
BLOOD_Lymphoma	Cytoplasmic translation →	+0.045	+0.262	<.001	.008	3	7
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.074	+0.376	.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,177 associations by consensus.

Peptidyl-amino acid modification by GRIA4 expression — LUNG_SCLC

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