GRIA1

Across TCGA cell cohorts, GRIA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 898 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GRIA1-associated GO terms across cancer lineages are Viral process, Biological process involved in symbiotic interaction, and Regulation of protein folding. Each is linked with GRIA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRIA1-to-partner and partner-to-GRIA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by GRIA1-low versus GRIA1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIA1→partner) and Y-score (partner→GRIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Viral process →	+0.043	+0.051	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Biological process involved in symbiotic interaction →	+0.085	+0.127	<.001	.008	3	4
LARGE_INTESTINE	Regulation of protein folding →	+0.064	+0.036	<.001	.005	3	4
LUNG_SCLC	Negative regulation of calcium ion export across plasma membrane →	+0.048	+2.449	<.001	<.001	3	4
LUNG_SCLC	Meiotic telomere tethering at nuclear periphery →	+0.131	+2.168	.003	<.001	3	4
LUNG_SCLC	Meiotic telomere clustering →	+0.131	+2.168	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 898 associations by consensus.

Viral process by GRIA1 expression — LARGE_INTESTINE

Explore this box plot interactively →