GRHL3

Across TCGA patient cohorts, GRHL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,887 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRHL3-associated proteins across cancer lineages are TACSTD2, PPL, and VSNL1. Each is linked with GRHL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRHL3-to-partner and partner-to-GRHL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRHL3 versus TACSTD2 in UCEC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRHL3→partner) and Y-score (partner→GRHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TACSTD2 →	+0.679	+1.064	<.001	<.001	3	5
HNSC	PPL →	+0.610	+1.089	<.001	<.001	3	5
UCEC	VSNL1 →	+1.417	+1.221	<.001	<.001	3	4
LSCC	NECTIN4_S426 →	+1.227	+1.765	<.001	<.001	3	4
LSCC	S100A2 →	+1.599	+1.736	.001	<.001	3	4
LSCC	SERPINB5 →	+1.182	+1.869	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,887 associations by consensus.

GRHL3 vs TACSTD2 — UCEC

Explore this scatter interactively →