GRHL2

Across TCGA patient cohorts, GRHL2 RNA expression is significantly associated with the RNA expression of many other genes, with 17,414 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GRHL2-associated genes across cancer lineages are EPN3, MAL2, and ESRP1. Each is linked with GRHL2 in more than 26 cancer types. Because this analysis shows association rather than direction, both GRHL2-to-partner and partner-to-GRHL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRHL2 versus EPN3 in UCS, with a Pearson correlation of 0.88.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRHL2→partner) and Y-score (partner→GRHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	EPN3 →	+2.296	+3.275	<.001	<.001	3	27
UCS	MAL2 →	+3.380	+3.200	<.001	<.001	3	26
UCS	ESRP1 →	+3.636	+3.580	<.001	<.001	3	26
UCS	EHF →	+2.980	+3.408	<.001	<.001	3	26
UCS	KDF1 →	+2.807	+3.080	<.001	<.001	3	26
TGCT	FAM83H →	+1.952	+1.745	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,414 associations by consensus.

GRHL2 vs EPN3 — UCS

Explore this scatter interactively →