GREB1L

Across TCGA cell cohorts, GREB1L mutation is significantly associated with the RNA expression of many other genes, with 1,031 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GREB1L-associated genes across cancer lineages are OR10R2, DEFB124, and PCMT1. Each is linked with GREB1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GREB1L-to-partner and partner-to-GREB1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by GREB1L-low versus GREB1L-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GREB1L→partner) and Y-score (partner→GREB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR10R2 →	+0.023	+4.786	<.001	.001	3	2
URINARY_TRACT	DEFB124 →	+0.137	+4.087	<.001	.009	3	2
LARGE_INTESTINE	PCMT1 →	+0.560	+2.829	.002	<.001	3	2
LARGE_INTESTINE	ENPP1 →	+0.896	+2.743	<.001	.001	3	2
PANCREAS	FCGR3B →	+0.024	+4.011	<.001	.009	3	1
PANCREAS	GAGE12E →	+0.035	+4.614	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,031 associations by consensus.

OR10R2 by GREB1L expression — PANCREAS

Explore this box plot interactively →