GRAMD4P6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRAMD4P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,107 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GRAMD4P6-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Regulation of striated muscle contraction, and Locomotory behavior. Each is linked with GRAMD4P6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD4P6-to-partner and partner-to-GRAMD4P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by GRAMD4P6-low versus GRAMD4P6-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD4P6→partner) and Y-score (partner→GRAMD4P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADNA replication-dependent chromatin assembly →+0.074+0.008<.001.00132
LAMLRegulation of striated muscle contraction →+0.047+0.105<.001<.00132
SKCMLocomotory behavior →+0.031+0.014.001<.00132
STADNegative regulation of hormone secretion →+0.078+0.033<.001.00432
STADCellular response to estradiol stimulus →+0.089+0.040<.001.00532
BRCARegulation of DNA damage checkpoint →+0.035+0.009.003<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

DNA replication-dependent chromatin assembly by GRAMD4P6 expression — BRCA

Box plot of DNA replication-dependent chromatin assembly in GRAMD4P6-low vs GRAMD4P6-high samples in BRCA.

Explore this box plot interactively →

Exploration