GRAMD1C

Across TCGA patient cohorts, GRAMD1C protein abundance is significantly associated with the RNA expression of many other genes, with 2,102 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRAMD1C-associated genes across cancer lineages are TMEM205, CDK15, and BDH2. Each is linked with GRAMD1C in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD1C-to-partner and partner-to-GRAMD1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD1C versus TMEM205 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD1C→partner) and Y-score (partner→GRAMD1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TMEM205 →	+1.231	+0.829	.001	.008	3	2
OV	CDK15 →	-0.845	-0.968	.009	.001	3	2
OV	BDH2 →	+0.831	+1.048	.001	.001	3	2
OV	GEN1 →	-0.979	-0.925	.002	<.001	3	2
LUAD	TUFM →	+0.523	+0.405	<.001	.002	3	2
GBM	ERBB4 →	+1.269	+0.473	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,102 associations by consensus.

GRAMD1C vs TMEM205 — OV

Explore this scatter interactively →