GRAMD1A

Across TCGA patient cohorts, GRAMD1A protein abundance is significantly associated with the RNA expression of many other genes, with 3,710 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRAMD1A-associated genes across cancer lineages are AMN, LRRC8E, and F12. Each is linked with GRAMD1A in more than 2 cancer types. Because this analysis shows association rather than direction, both GRAMD1A-to-partner and partner-to-GRAMD1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD1A versus AMN in PDAC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD1A→partner) and Y-score (partner→GRAMD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AMN →	-0.999	-0.419	<.001	<.001	3	3
LSCC	LRRC8E →	-0.346	-0.201	.001	<.001	3	3
LSCC	F12 →	-0.953	-0.349	<.001	<.001	3	2
LSCC	ABHD15 →	-0.477	-0.215	.001	.009	3	2
LSCC	MAPK12 →	-0.685	-0.268	.001	.004	3	2
CCRCC	MIR580 →	+0.875	+0.369	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,710 associations by consensus.

GRAMD1A vs AMN — PDAC

Explore this scatter interactively →