Across TCGA patient cohorts, GPX6 RNA expression is significantly associated with the RNA expression of many other genes, with 3,986 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GPX6-associated genes across cancer lineages are MED15P8, NF1P8, and SSX8P. Each is linked with GPX6 in more than 11 cancer types. Because this analysis shows association rather than direction, both GPX6-to-partner and partner-to-GPX6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX6→partner) and Y-score (partner→GPX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	MED15P8 →	+0.664	+0.146	<.001	<.001	3	12
ESCA	NF1P8 →	+0.688	+0.146	<.001	.001	3	11
KICH	SSX8P →	+1.932	+0.046	<.001	<.001	3	11
KICH	MAGEB1 →	+1.559	+0.069	<.001	<.001	3	10
KICH	LINC01855 →	+0.959	+0.046	<.001	<.001	3	10
TGCT	LRRC37A12P →	+0.577	+0.091	.002	.008	1	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,986 associations by consensus.

Exploration

GPX6 survival (RNA) · tumor vs normal (RNA) · all GPX6 data types