Across TCGA patient cohorts, GPX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,348 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPX3-associated proteins across cancer lineages are ADH1B, F13A1, and CAVIN2. Each is linked with GPX3 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPX3-to-partner and partner-to-GPX3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX3→partner) and Y-score (partner→GPX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADH1B →	+1.461	+1.694	.001	<.001	3	7
GBM	F13A1 →	+0.950	+1.276	<.001	<.001	3	7
BRCA	CAVIN2 →	+0.907	+1.485	<.001	<.001	3	6
COAD	FABP4 →	+1.197	+1.034	<.001	<.001	3	6
BRCA	FHL1 →	+1.010	+1.495	<.001	<.001	3	6
GBM	AOX1 →	+0.766	+1.308	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,348 associations by consensus.

Exploration

GPX3 survival (RNA) · tumor vs normal (RNA) · all GPX3 data types