GPS2

Across TCGA patient cohorts, GPS2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,217 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPS2-associated genes across cancer lineages are RPA1, TADA1, and RIC8B. Each is linked with GPS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPS2-to-partner and partner-to-GPS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPS2 versus RPA1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPS2→partner) and Y-score (partner→GPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPA1 →	+0.576	+0.289	<.001	<.001	3	5
LSCC	TADA1 →	+0.649	+0.337	<.001	<.001	3	5
LSCC	RIC8B →	+0.419	+0.195	<.001	<.001	3	5
HNSC	NUP88 →	+0.405	+0.169	<.001	<.001	3	4
LSCC	BCL7A →	+0.532	+0.159	<.001	<.001	3	4
LSCC	RFC5 →	+0.833	+0.299	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,217 associations by consensus.

GPS2 vs RPA1 — HNSC

Explore this scatter interactively →