GPS2

Across TCGA cell cohorts, GPS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,005 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPS2-associated GO terms across cancer lineages are Telomere assembly, U2-type prespliceosome assembly, and Chromosome segregation. Each is linked with GPS2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GPS2-to-partner and partner-to-GPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by GPS2-low versus GPS2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPS2→partner) and Y-score (partner→GPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.152	+0.856	<.001	<.001	3	15
BONE	U2-type prespliceosome assembly →	+0.107	+0.668	.005	.004	3	14
BONE	Chromosome segregation →	+0.135	+0.679	.005	.005	3	14
LARGE_INTESTINE	Regulation of establishment of protein localization to telomere →	+0.111	+0.596	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of translation at presynapse →	+0.144	+1.065	<.001	.001	3	13
BONE	Regulation of translation at synapse, modulating synaptic transmission →	+0.148	+0.868	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,005 associations by consensus.

Telomere assembly by GPS2 expression — LUNG_SCLC

Explore this box plot interactively →