Across TCGA cell cohorts, GPRIN2 mutation is significantly associated with the RNA expression of many other genes, with 325 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPRIN2-associated genes across cancer lineages are SLCO1C1, OR2J3, and ADAM30. Each is linked with GPRIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPRIN2-to-partner and partner-to-GPRIN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN2→partner) and Y-score (partner→GPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SLCO1C1 →	+0.190	+4.199	<.001	.007	3	2
BLOOD_Leukemia	OR2J3 →	+0.019	+3.007	.006	.007	3	2
BLOOD_Myeloma	ADAM30 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	IFNA4 →	+0.033	+4.807	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	OC90 →	+0.006	+5.357	<.001	.003	3	1
LARGE_INTESTINE	ANKRD54 →	+0.534	+3.451	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 325 associations by consensus.

Exploration

GPRIN2 survival (RNA) · tumor vs normal (RNA) · all GPRIN2 data types