GPRIN1

Across TCGA patient cohorts, GPRIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,093 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPRIN1-associated genes across cancer lineages are RHBDL3, GLT1D1, and TMCO4. Each is linked with GPRIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPRIN1-to-partner and partner-to-GPRIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRIN1 versus RHBDL3 in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN1→partner) and Y-score (partner→GPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RHBDL3 →	+1.080	+0.625	<.001	<.001	3	3
GBM	GLT1D1 →	+1.101	+0.800	<.001	<.001	3	3
BRCA	TMCO4 →	-0.437	-0.475	<.001	<.001	3	3
GBM	INTS7 →	+0.568	+0.827	<.001	<.001	3	3
BRCA	CHRNB2 →	+1.244	+0.492	<.001	.003	3	3
BRCA	IGHA1 →	-1.865	-0.479	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,093 associations by consensus.

GPRIN1 vs RHBDL3 — GBM

Explore this scatter interactively →