GPRC5D

Across TCGA patient cohorts, GPRC5D RNA expression is significantly associated with the protein abundance of many other proteins, with 10,969 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPRC5D-associated proteins across cancer lineages are PCYT1A_S331, NAB2_S171, and NAB2_S6. Each is linked with GPRC5D in more than 3 cancer types. Because this analysis shows association rather than direction, both GPRC5D-to-partner and partner-to-GPRC5D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5D versus PCYT1A_S331 in LUAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5D→partner) and Y-score (partner→GPRC5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PCYT1A_S331 →	+1.029	+0.578	.001	<.001	3	3
LSCC	NAB2_S171 →	+0.753	+1.357	<.001	<.001	3	3
LSCC	NAB2_S6 →	+0.681	+1.193	<.001	<.001	3	3
HNSC	NIP7 →	+0.302	+1.144	<.001	<.001	3	3
HNSC	MYH14 →	+0.655	+1.254	<.001	<.001	3	3
HNSC	MYH14_T1462 →	+1.019	+1.225	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,969 associations by consensus.

GPRC5D vs PCYT1A_S331 — LUAD

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