GPRC5D

Across TCGA patient cohorts, GPRC5D protein abundance is significantly associated with the protein abundance of many other proteins, with 20,744 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPRC5D-associated proteins across cancer lineages are CD53, DOCK2, and ELMO1. Each is linked with GPRC5D in more than 9 cancer types. Because this analysis shows association rather than direction, both GPRC5D-to-partner and partner-to-GPRC5D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5D versus CD53 in BRCA, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5D→partner) and Y-score (partner→GPRC5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD53 →	+1.227	+1.163	<.001	<.001	3	9
OV	DOCK2 →	+0.634	+0.635	.001	.002	2	10
BRCA	ELMO1 →	+0.574	+0.921	<.001	<.001	3	9
UCEC	IL16 →	+0.695	+0.586	<.001	<.001	3	9
UCEC	APBB1IP →	+0.745	+0.600	<.001	<.001	3	9
GBM	NCKAP1L →	+0.653	+0.494	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,744 associations by consensus.

GPRC5D vs CD53 — BRCA

Explore this scatter interactively →