GPRC5D

Across TCGA cell cohorts, GPRC5D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,042 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPRC5D-associated GO terms across cancer lineages are Post-transcriptional gene silencing, Regulatory ncRNA-mediated post-transcriptional gene silencing, and Fibroblast migration. Each is linked with GPRC5D in more than 8 cancer types. Because this analysis shows association rather than direction, both GPRC5D-to-partner and partner-to-GPRC5D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-transcriptional gene silencing grouped by GPRC5D-low versus GPRC5D-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5D→partner) and Y-score (partner→GPRC5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Post-transcriptional gene silencing →	+0.093	+1.105	<.001	<.001	3	9
LARGE_INTESTINE	Regulatory ncRNA-mediated post-transcriptional gene silencing →	+0.069	+0.967	<.001	<.001	3	7
BREAST	Fibroblast migration →	+0.115	+0.796	.005	.006	3	6
LARGE_INTESTINE	Nucleic acid catabolic process →	+0.028	+0.582	.001	<.001	3	6
LARGE_INTESTINE	Regulation of ruffle assembly →	+0.094	+0.589	.008	.007	3	6
STOMACH	Protein targeting →	+0.063	+0.915	.005	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,042 associations by consensus.

Post-transcriptional gene silencing by GPRC5D expression — LARGE_INTESTINE

Explore this box plot interactively →