GPRC5A

Across TCGA patient cohorts, GPRC5A protein abundance is significantly associated with the RNA expression of many other genes, with 15,368 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPRC5A-associated genes across cancer lineages are VGLL1, SCEL, and AGR2. Each is linked with GPRC5A in more than 4 cancer types. Because this analysis shows association rather than direction, both GPRC5A-to-partner and partner-to-GPRC5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5A versus VGLL1 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5A→partner) and Y-score (partner→GPRC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VGLL1 →	+1.563	+0.881	<.001	<.001	3	5
OV	SCEL →	+1.658	+1.121	<.001	<.001	3	5
BRCA	AGR2 →	+2.850	+0.825	<.001	<.001	3	4
OV	PERP →	+1.070	+1.270	.002	<.001	3	4
OV	TTC9 →	+1.045	+0.736	<.001	.003	3	4
UCEC	MALL →	+1.201	+1.019	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,368 associations by consensus.

GPRC5A vs VGLL1 — OV

Explore this scatter interactively →