Across TCGA patient cohorts, GPRASP1 mutation is significantly associated with the RNA expression of many other genes, with 4,389 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPRASP1-associated genes across cancer lineages are MED8, GHITM, and DHDDS. Each is linked with GPRASP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPRASP1-to-partner and partner-to-GPRASP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRASP1→partner) and Y-score (partner→GPRASP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MED8 →	+0.250	+1.445	<.001	<.001	3	4
UCEC	GHITM →	+0.430	+2.054	<.001	<.001	3	4
UCEC	DHDDS →	+0.321	+1.711	<.001	<.001	3	4
UCEC	DCLRE1B →	+0.477	+2.665	<.001	<.001	3	4
UCEC	EMC6 →	+0.462	+2.137	<.001	<.001	3	4
UCEC	GCH1 →	+0.481	+1.161	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Exploration

GPRASP1 survival (RNA) · tumor vs normal (RNA) · all GPRASP1 data types