Across TCGA pan-cancer cohorts, GPR89P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of GPR89P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where GPR89P RNA is repressed in tumor relative to normal tissue. In most cancer types GPR89P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
KICH, LUAD, and LUSC are the cancer types where GPR89P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPR89P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.