G protein-coupled receptor 89 pseudogeneGenealiases: []
Q-omics provides the consensus-scored GPR89P profile across patient tissues and cancer cell-line models. GPR89P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, GPR89P is differentially expressed in 8, with the highest sampling consensus in KICH. Additionally, GPR89P RNA expression shows 13,431 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, and THYM as cancer lineages where GPR89P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GPR89P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GPR89P survival associations across molecular data types. GPR89P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GPR89P RNA expression–survival associations across cancer types. High GPR89P expression shows unfavorable associations in KICH, LIHC, KIRC, STAD and CHOL, but favorable associations in SKCM. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for GPR89P RNA expression.
This table summarizes GPR89P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for GPR89P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GPR89P shows lower tumor expression in KICH and KIRC and higher tumor expression in LUAD, LUSC, STAD and HNSC. The KICH box plot shows higher GPR89P RNA expression in normal versus tumor tissue (log2 FC = −0.349, t-test p < 0.001).
This table shows molecular features associated with GPR89P in patient tissues and cancer cell lines. In patient samples, GPR89P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
