Across TCGA cell cohorts, GPR89B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR89B-associated genes across cancer lineages are APOC3, MTNR1B, and C14orf180. Each is linked with GPR89B in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR89B-to-partner and partner-to-GPR89B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR89B→partner) and Y-score (partner→GPR89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	APOC3 →	+2.502	+3.793	<.001	.007	3	1
LARGE_INTESTINE	MTNR1B →	+0.313	+3.684	.001	.006	3	1
LARGE_INTESTINE	C14orf180 →	+0.133	+4.155	<.001	.003	3	1
LARGE_INTESTINE	CLPSL1 →	+0.119	+4.054	.001	.004	3	1
LARGE_INTESTINE	KRTAP10-3 →	+0.054	+3.920	<.001	.005	3	1
LARGE_INTESTINE	CSH2 →	+0.285	+3.920	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GPR89B survival (RNA) · tumor vs normal (RNA) · all GPR89B data types