GPR87

Across TCGA cell cohorts, GPR87 mutation is significantly associated with the mutation status of many other genes, with 3,040 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR87-associated genes across cancer lineages are ASB15, OTOF, and RIPOR1. Each is linked with GPR87 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR87-to-partner and partner-to-GPR87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB15 grouped by GPR87-low versus GPR87-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR87→partner) and Y-score (partner→GPR87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ASB15 →	+4.239	+5.053	.007	.007	1	4
BLOOD_Lymphoma	OTOF →	+3.362	+4.754	.002	.002	1	3
LUNG_NSCLC_LUAD	RIPOR1 →	+5.339	+4.772	.004	.004	1	3
LUNG_NSCLC_LUAD	PHLPP2 →	+5.339	+4.772	.004	.004	1	3
BLOOD_Lymphoma	LETMD1 →	+4.584	+4.584	.007	.007	1	3
LUNG_NSCLC_LUAD	ACTN2 →	+2.924	+4.334	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,040 associations by consensus.

ASB15 by GPR87 expression — SKIN

Explore this box plot interactively →