GPR85

Across TCGA patient cohorts, GPR85 mutation is significantly associated with the RNA expression of many other genes, with 2,921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR85-associated genes across cancer lineages are LINC01072, RNU6-758P, and RNA5SP412. Each is linked with GPR85 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR85-to-partner and partner-to-GPR85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by GPR85-low versus GPR85-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR85→partner) and Y-score (partner→GPR85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01072 →	+0.219	+5.345	<.001	.001	3	3
LUAD	RNU6-758P →	+0.438	+2.431	.004	.006	3	3
UCEC	RNA5SP412 →	+0.415	+1.534	<.001	.004	3	3
UCEC	RCC1 →	+0.368	+2.185	.004	<.001	3	2
UCEC	INSIG1 →	+0.562	+2.119	.001	.002	3	2
UCEC	FANCA →	+0.707	+1.857	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,921 associations by consensus.

LINC01072 by GPR85 expression — CESC

Explore this box plot interactively →