GPR82

Across TCGA patient cohorts, GPR82 mutation is significantly associated with the RNA expression of many other genes, with 1,794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR82-associated genes across cancer lineages are RNU6-709P, MIR367, and RNU6-782P. Each is linked with GPR82 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR82-to-partner and partner-to-GPR82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-709P grouped by GPR82-low versus GPR82-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR82→partner) and Y-score (partner→GPR82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-709P →	+0.483	+7.816	<.001	.008	3	3
CESC	MIR367 →	+0.565	+4.551	.001	.004	3	2
LUAD	RNU6-782P →	+0.521	+5.197	<.001	.003	3	2
COAD	IGHD4-4 →	+2.045	+5.357	<.001	.006	3	2
LUSC	RNU4-13P →	+0.219	+4.496	<.001	.007	3	2
LUSC	NDUFB10P1 →	+0.393	+4.184	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

RNU6-709P by GPR82 expression — SKCM

Explore this box plot interactively →