GPR63

Across TCGA patient cohorts, GPR63 protein abundance is significantly associated with the RNA expression of many other genes, with 1,596 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPR63-associated genes across cancer lineages are SLC25A17, PMPCB, and GBE1. Each is linked with GPR63 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR63-to-partner and partner-to-GPR63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR63 versus SLC25A17 in GBM, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR63→partner) and Y-score (partner→GPR63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC25A17 →	+0.773	+0.473	.004	.005	2	3
HNSC	PMPCB →	+0.866	+0.671	.007	.001	3	2
HNSC	GBE1 →	+0.706	+0.576	.002	.002	3	2
HNSC	PCGF6 →	+0.644	+0.588	<.001	<.001	3	2
HNSC	MAGOH →	+0.712	+0.486	.003	.003	3	2
LSCC	PRDX3 →	+0.554	+0.679	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,596 associations by consensus.

GPR63 vs SLC25A17 — GBM

Explore this scatter interactively →