GPR61

Across TCGA pan-cancer cohorts, GPR61 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GPR61 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher GPR61 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR61 expression acts as an unfavorable survival marker.

BLCA, HNSC, and LIHC are the cancer types where GPR61 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.174	0.625	.023	12	view →
HNSC	OS	Median	All	0.508	0.769	.020	12	view →
LIHC	OS	Median	All	0.255	0.773	.012	6	view →
COAD	OS	Median	II,III,IV	0.001	0.860	<.001	6	view →
SKCM	OS	Median	II,III,IV	0.153	0.399	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GPR61–BLCA (DFS)

Open the BLCA breakdown →