GPR61

Across TCGA patient cohorts, GPR61 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,484 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR61-associated proteins across cancer lineages are RPL26, RRBP1, and FKBP11. Each is linked with GPR61 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR61-to-partner and partner-to-GPR61 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR61 versus RPL26 in PDAC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR61→partner) and Y-score (partner→GPR61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPL26 →	-0.444	-0.134	.003	<.001	3	4
GBM	RRBP1 →	-0.418	-0.543	<.001	<.001	3	4
GBM	FKBP11 →	-0.645	-0.425	<.001	<.001	3	4
LSCC	GOLGA3_S22 →	-0.572	-0.260	<.001	.006	3	4
GBM	HDLBP →	-0.296	-0.588	<.001	<.001	3	4
PDAC	DNAJC1 →	-0.344	-0.162	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,484 associations by consensus.

GPR61 vs RPL26 — PDAC

Explore this scatter interactively →