Across TCGA patient cohorts, GPR52 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,877 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GPR52-associated proteins across cancer lineages are RABGAP1L, RPRD2, and ARHGEF11. Each is linked with GPR52 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPR52-to-partner and partner-to-GPR52 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR52→partner) and Y-score (partner→GPR52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RABGAP1L →	+0.251	+0.481	<.001	<.001	3	6
GBM	RPRD2 →	+0.295	+0.435	<.001	<.001	3	5
UCEC	ARHGEF11 →	+0.232	+0.648	.001	<.001	3	5
LSCC	POGZ →	+0.213	+0.314	.006	.003	3	5
LSCC	SIN3A →	+0.166	+0.322	.006	.002	3	4
GBM	ARID4B →	+0.211	+0.325	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,877 associations by consensus.

Exploration

GPR52 survival (RNA) · tumor vs normal (RNA) · all GPR52 data types