GPR45

Across TCGA patient cohorts, GPR45 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,319 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR45-associated proteins across cancer lineages are RPL7, EPB41L3_S88, and FNBP4_T517. Each is linked with GPR45 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR45-to-partner and partner-to-GPR45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR45 versus RPL7 in GBM, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR45→partner) and Y-score (partner→GPR45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.340	-0.462	.002	.001	3	3
GBM	EPB41L3_S88 →	+0.730	+0.526	.006	.003	3	3
OV	FNBP4_T517 →	-1.279	-0.249	.001	.002	3	3
LSCC	TLN1_S979 →	-0.849	-0.335	<.001	<.001	3	2
PDAC	PCSK1N →	+0.903	+0.212	<.001	<.001	3	2
GBM	PDIA5 →	-0.563	-0.480	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,319 associations by consensus.

GPR45 vs RPL7 — GBM

Explore this scatter interactively →