GPR45

Across TCGA cell cohorts, GPR45 protein abundance is significantly associated with the RNA expression of many other genes, with 1,572 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GPR45-associated genes across cancer lineages are IFFO2, DPYSL2, and C16orf71. Each is linked with GPR45 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR45-to-partner and partner-to-GPR45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR45 versus IFFO2 in BLOOD_Lymphoma, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR45→partner) and Y-score (partner→GPR45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	IFFO2 →	+1.770	+0.703	.009	.001	3	4
BLOOD_Lymphoma	DPYSL2 →	+2.105	+0.902	<.001	.001	2	5
SKIN	C16orf71 →	+0.368	+0.823	.005	.008	3	4
BLOOD_Lymphoma	ATP2C1 →	+1.130	+0.810	.006	.007	3	4
OESOPHAGUS	RNF24 →	+0.553	+0.952	.001	.002	3	4
BLOOD_Leukemia	CHKB →	+0.599	+0.607	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,572 associations by consensus.

GPR45 vs IFFO2 — BLOOD_Lymphoma

Explore this scatter interactively →