Across TCGA patient cohorts, GPR39 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,930 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR39-associated proteins across cancer lineages are TBXAS1, PNKD, and GPR39_S380. Each is linked with GPR39 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR39-to-partner and partner-to-GPR39 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR39→partner) and Y-score (partner→GPR39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TBXAS1 →	+0.925	+1.514	.001	<.001	3	4
CCRCC	PNKD →	+0.708	+0.762	<.001	<.001	3	4
GBM	GPR39_S380 →	+3.076	+1.814	.001	<.001	3	4
UCEC	SRRT →	-0.285	-0.764	<.001	<.001	3	3
UCEC	STING1 →	+0.684	+0.735	<.001	<.001	3	3
LSCC	UNC13D →	+0.430	+0.420	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,930 associations by consensus.

Exploration

GPR39 survival (RNA) · tumor vs normal (RNA) · all GPR39 data types