GPR37L1

Across TCGA patient cohorts, GPR37L1 mutation is significantly associated with the RNA expression of many other genes, with 1,167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR37L1-associated genes across cancer lineages are RPL29P32, TAS2R8, and RN7SKP65. Each is linked with GPR37L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR37L1-to-partner and partner-to-GPR37L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL29P32 grouped by GPR37L1-low versus GPR37L1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR37L1→partner) and Y-score (partner→GPR37L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL29P32 →	+0.058	+4.562	<.001	.006	3	3
HNSC	TAS2R8 →	+0.063	+3.916	<.001	.006	3	2
HNSC	RN7SKP65 →	+0.239	+4.449	<.001	.002	3	2
HNSC	RAB28P1 →	+0.058	+5.547	<.001	.001	3	2
HNSC	MTND5P19 →	+0.023	+3.952	<.001	.005	3	2
HNSC	SALL4P5 →	+0.045	+4.280	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,167 associations by consensus.

RPL29P32 by GPR37L1 expression — BLCA

Explore this box plot interactively →