Across TCGA cell cohorts, GPR33 RNA expression is significantly associated with the drug of many other genes, with 104 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GPR33-associated genes across cancer lineages are CPI-637, Vorinostat, and Pevonedistat. Each is linked with GPR33 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR33-to-partner and partner-to-GPR33 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR33→partner) and Y-score (partner→GPR33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CPI-637 →	-0.575	-0.012	.029	.032	3	4
LUNG_NSCLC_LUAD	Vorinostat →	-0.727	-0.005	.001	.031	3	3
LUNG_NSCLC_LUAD	Pevonedistat →	-0.816	-0.005	.045	.031	3	3
LUNG_NSCLC_LUAD	Telomerase Inhibitor IX →	-0.601	-0.005	.007	.031	3	3
LUNG_SCLC	BMS-536924 →	-0.428	-0.015	.032	.026	3	3
LUNG_SCLC	MN-64 →	-0.490	-0.020	.007	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

Exploration

GPR33 survival (RNA) · tumor vs normal (RNA) · all GPR33 data types