GPR31

Across TCGA patient cohorts, GPR31 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,888 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR31-associated proteins across cancer lineages are INPP5D, VAV1, and SAMHD1. Each is linked with GPR31 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR31-to-partner and partner-to-GPR31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR31 versus INPP5D in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR31→partner) and Y-score (partner→GPR31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	INPP5D →	+0.586	+0.208	<.001	<.001	3	9
GBM	VAV1 →	+0.516	+0.233	.003	.002	3	8
HNSC	SAMHD1 →	+0.584	+0.337	<.001	.002	3	8
HNSC	HCLS1 →	+0.668	+0.327	<.001	.005	3	8
HNSC	GIMAP4 →	+0.528	+0.193	<.001	.002	3	8
HNSC	WDFY4 →	+0.570	+0.336	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,888 associations by consensus.

GPR31 vs INPP5D — LSCC

Explore this scatter interactively →