GPR31

Across TCGA patient cohorts, GPR31 protein abundance is significantly associated with the RNA expression of many other genes, with 15,674 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR31-associated genes across cancer lineages are MYL9, MEDAG, and ACTA2. Each is linked with GPR31 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPR31-to-partner and partner-to-GPR31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR31 versus MYL9 in UCEC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR31→partner) and Y-score (partner→GPR31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.447	+0.794	<.001	<.001	3	10
OV	MEDAG →	+1.896	+1.172	<.001	<.001	3	10
OV	ACTA2 →	+2.330	+1.402	<.001	<.001	3	10
BRCA	CALD1 →	+1.344	+1.039	<.001	<.001	3	10
CCRCC	ISLR →	+1.862	+1.267	<.001	<.001	3	10
UCEC	CNN1 →	+2.908	+1.102	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,674 associations by consensus.

GPR31 vs MYL9 — UCEC

Explore this scatter interactively →