GPR31

Across TCGA cell cohorts, GPR31 RNA expression is significantly associated with the mutation status of many other genes, with 40 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPR31-associated genes across cancer lineages are TACC2, NBR1, and RIMS1. Each is linked with GPR31 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR31-to-partner and partner-to-GPR31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TACC2 grouped by GPR31-low versus GPR31-high in OESOPHAGUS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR31→partner) and Y-score (partner→GPR31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TACC2 →	+4.906	+0.016	.006	<.001	3	2
OESOPHAGUS	NBR1 →	+4.906	+0.016	.006	<.001	3	2
LUNG_SCLC	RIMS1 →	+2.847	+0.016	.009	<.001	3	1
OESOPHAGUS	ARHGAP15 →	+4.906	+0.016	.006	<.001	3	1
OESOPHAGUS	NPR3 →	+4.906	+0.016	.006	<.001	3	1
OESOPHAGUS	KCNH3 →	+4.906	+0.016	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

TACC2 by GPR31 expression — OESOPHAGUS

Explore this box plot interactively →