GPR27

Across TCGA patient cohorts, GPR27 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,132 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPR27-associated proteins across cancer lineages are MTA1, MTARC2, and PKP4. Each is linked with GPR27 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR27-to-partner and partner-to-GPR27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR27 versus MTA1 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR27→partner) and Y-score (partner→GPR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA1 →	+0.300	+0.858	.001	<.001	3	3
LUAD	MTARC2 →	+0.395	+0.582	<.001	<.001	3	3
GBM	PKP4 →	+0.357	+1.201	<.001	<.001	3	3
GBM	PKP4_S776 →	+0.690	+0.867	.002	.007	3	3
COAD	ZCCHC24 →	+0.709	+0.360	<.001	.001	3	3
HNSC	TCEAL1 →	+0.468	+1.210	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,132 associations by consensus.

GPR27 vs MTA1 — LSCC

Explore this scatter interactively →