Across TCGA cell cohorts, GPR19 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR19-associated genes across cancer lineages are RGS21, CFAP47, and OR2D2. Each is linked with GPR19 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR19-to-partner and partner-to-GPR19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR19→partner) and Y-score (partner→GPR19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RGS21 →	+0.006	+5.781	<.001	.001	3	1
LARGE_INTESTINE	CFAP47 →	+0.198	+3.453	.008	.009	3	1
LARGE_INTESTINE	OR2D2 →	+0.053	+3.554	.003	.007	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ADIPOQ →	+0.007	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ACTL7A →	+0.032	+4.145	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GPR19 survival (RNA) · tumor vs normal (RNA) · all GPR19 data types