GPR182

Across TCGA patient cohorts, GPR182 mutation is significantly associated with the RNA expression of many other genes, with 442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR182-associated genes across cancer lineages are KATNBL1P4, SNORD90, and PINCR. Each is linked with GPR182 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR182-to-partner and partner-to-GPR182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KATNBL1P4 grouped by GPR182-low versus GPR182-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR182→partner) and Y-score (partner→GPR182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KATNBL1P4 →	+0.055	+5.087	.007	.002	3	2
UCEC	SNORD90 →	+0.350	+2.840	<.001	<.001	3	2
UCEC	PINCR →	+0.301	+2.127	<.001	.006	3	2
SKCM	TFAMP2 →	+0.078	+4.454	<.001	.002	3	2
SKCM	IDH2-DT →	+0.300	+3.819	<.001	.009	3	2
SKCM	LINC02210-CRHR1 →	+0.077	+3.838	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 442 associations by consensus.

KATNBL1P4 by GPR182 expression — COAD

Explore this box plot interactively →